Anyone who is interested in boosting NAD levels through supplementation will quickly run across the precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR). Both have great track records in supporting healthy aging, but there are differences between the two molecules. nr vs nmn are different because they work differently in the body to increase NAD+.
Does NMN increase testosterone?
NR is an immediate precursor to NAD+, whereas NMN needs to be converted into NR before it can enter cells to promote NAD biosynthesis. NMN is a bigger molecule than NR and thus must pass through cell membranes via specialized transporter molecules that act like oversized doorways. NMN has more of these transporter molecules than NR, which may explain why it’s been less effective in clinical trials.
In a new study, researchers found that orally administered NMN significantly increased NAD+ in the blood.21 They believe that this increase may be due to a direct effect of NMN on cellular metabolism, as opposed to the indirect effects of NR, which requires conversion into NAD+ in a cell’s mitochondria.
Regardless, both NR and NMN have been proven to be potent NAD+ precursors, increasing NAD+ in the blood and supporting healthy DNA. Wonderfeel currently offers a highly bioavailable nr vs nmn product, our Basis supplement, which contains NR and pterostilbene to support cellular health and longevity through NAD+ activation. If you want to try nr vs nmn, we recommend taking Basis in liposomes for optimal absorption and efficacy.