Recombinant protein expression and purification services involves creating proteins with a high level of purity and consistency. This allows for greater control in experimental applications and in drug manufacturing, especially when large volumes of the protein are required. Recombinant proteins can be produced in a number of different host cells, including bacteria, yeast, and mammalian (specifically Chinese hamster ovary, or CHO) cells.
This method of production can be particularly useful for producing antibodies against a particular recombinant protein, or creating new antibodies with higher binding capabilities or affinities. Businesses specializing in antibody sequencing can also provide services for this purpose.
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Another advantage of recombinant protein creation is its speed, which is important for applications like diagnostics and therapies that require fast responses. The most common protein expression systems include bacterial, baculovirus/insect, and mammalian (CHO) cell lines. This gives researchers plenty of choice, allowing them to find the right system for their experiment.